Retrovir is an anti-HIV-1 medication. It contains active substance zidovudine which is a reverse transcriptase inhibitor. This class of medications also includes zalcitabine (Hivid), didanosine (Videx), and lamivudine (Epivir), stavudine (Zerit). Retrovir increases production of T4 cells and hereby increases resistance to infection. Its ability to inhibit reverse transcriptase of HIV is 100-300 times bigger than its ability to inhibit human DNA polymerase. Retrovir is produced to treat HIV infection in adults and children over 3 months of age with symptoms of the diseases or ones with no symptoms but a significant evidence of impaired immunity.

Dosage and direction

The recommended dose for adults is 100 mg taken every for hours. Optimal dose is 0.5-1.5 g a day. Blood cell count should be monitored on a regular basis and treatment should be interrupted if level of Hb decreases 25% and one of neutrophils does 50% from the initial level. In children under 12 years of age initial dose is counted as 180 mg per every square meter each 6 hours but not more than 200 mg every 6 hours. To prevent HIV transmission to the baby from the mother 100 mg of Retrovir is given five times daily until the time of labor starting from 14th week of pregnancy.

Contraindications

Retrovir cannot be used in individuals with hypersensitivity to the medication, anemia.

Possible side effect

The most serious side effects include a decrease in blood cells, myopathy, enlarged liver and lactic acidosis. Other adverse reactions are: fatigue, headache, asthenia, drowsiness, pain in the heart, stomach, vomiting, nausea, diarrhea, gas, depression, fever symptoms, cough, secondary infection. Only your doctor is able to decide if it is safe for you to take Retrovir. Check with your doctor if the symptoms listed above become bothersome or change in intensity.

Drug interaction

Paracetamol inhibits metabolism of Retrovir and this way increases a risk of neutropenia. Retrovir plasma levels are inhibited by inhibitors of microsomal oxidation in the liver such as morphine, codeine, indomethacin, oxazepam, cimetidine, klofibrat. Pentamidine, amphotericin B, ganciclovir, vincristine, vinblastine, radiation therapy increase toxic effects of Retrovir. Retrovir increases blood concentration of fluconazole. Ribavirin inhibits biochemical activation of Retrovir in the body and not recommended for concomitant therapy. Stavudine, Combivir or Trizivir cannot be used together with Retrovir.

Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Overdose

Any medication taken in the excessive quantity maybe dangerous. If you suspect overdose and experience fatigue, nausea, headache, vomiting seek immediate medical attention.

Storage

Retrovir should be stored at room temperature between 15-30 C (59-86 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Retrovir is an anti-HIV-1 medication. It contains active substance zidovudine which is a reverse transcriptase inhibitor. This class of medications also includes zalcitabine (Hivid), didanosine (Videx), and lamivudine (Epivir), stavudine (Zerit). Retrovir increases production of T4 cells and hereby increases resistance to infection. Its ability to inhibit reverse transcriptase of HIV is 100-300 times bigger than its ability to inhibit human DNA polymerase. Retrovir is produced to treat HIV infection in adults and children over 3 months of age with symptoms of the diseases or ones with no symptoms but a significant evidence of impaired immunity.

Dosage and direction

The recommended dose for adults is 100 mg taken every for hours. Optimal dose is 0.5-1.5 g a day. Blood cell count should be monitored on a regular basis and treatment should be interrupted if level of Hb decreases 25% and one of neutrophils does 50% from the initial level. In children under 12 years of age initial dose is counted as 180 mg per every square meter each 6 hours but not more than 200 mg every 6 hours. To prevent HIV transmission to the baby from the mother 100 mg of Retrovir is given five times daily until the time of labor starting from 14th week of pregnancy.

Precautions

Risk of an enlarged liver and lactic acidosis increases during treatment with Retrovir especially overweight patients and those whose treatment continued for a rather extended period. If such condition develops treatment with Retrovir should be discontinued. Contact your doctor immediately if you experience such symptoms as fatigue, abdominal pain, nausea, feeling of unwellness. Cautiousness should be exercised in patients with a bone marrow disease or reduced amount of T-helpers, reduced bone marrow reserve prior to treatment, neutropenia, anemia, vitamin B12 deficiency. Drugs for HIV may cause a redistribution of body fat: (a “buffalo hump” on the back, extra fat around the middle, and wasting in the arms, legs, and face).

Contraindications

Retrovir cannot be used in individuals with hypersensitivity to the medication, anemia.

Possible side effect

The most serious side effects include a decrease in blood cells, myopathy, enlarged liver and lactic acidosis. Other adverse reactions are: fatigue, headache, asthenia, drowsiness, pain in the heart, stomach, vomiting, nausea, diarrhea, gas, depression, fever symptoms, cough, secondary infection. Only your doctor is able to decide if it is safe for you to take Retrovir. Check with your doctor if the symptoms listed above become bothersome or change in intensity.

Drug interaction

Paracetamol inhibits metabolism of Retrovir and this way increases a risk of neutropenia. Retrovir plasma levels are inhibited by inhibitors of microsomal oxidation in the liver such as morphine, codeine, indomethacin, oxazepam, cimetidine, klofibrat. Pentamidine, amphotericin B, ganciclovir, vincristine, vinblastine, radiation therapy increase toxic effects of Retrovir. Retrovir increases blood concentration of fluconazole. Ribavirin inhibits biochemical activation of Retrovir in the body and not recommended for concomitant therapy. Stavudine, Combivir or Trizivir cannot be used together with Retrovir.

Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Overdose

Any medication taken in the excessive quantity maybe dangerous. If you suspect overdose and experience fatigue, nausea, headache, vomiting seek immediate medical attention.

Storage

Retrovir should be stored at room temperature between 15-30 C (59-86 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

The recommended dose for adults is 600 mg taken once daily. The daily dose for children with weight of 13-15 kg is 200 mg, for ones with 5-20 kg is 250 mg, for ones with 20-25 kg is 300 mg, for ones with 25?32,5 kg is 350 mg, for ones with 32,5?40 kg is 400 mg. Individuals with body weight over 40 kg should take 600 mg of Sustiva. First two weeks take the medication before your bedtime.

Precautions

Inform your doctor if you have liver or kidney failure, alcohol or drug addicted, encephalopathy, high cholesterol or triglycerides, liver disease (including hepatitis B or C), if you have ever taken delavirdine (Rescriptor) or nevirapine (Viramune) without any therapeutic result. Cautiousness should be exercised in children under 3 years of age, and children with body weight under 13 kg. Use reliable contraception while you are on Sustiva as this medication may cause serious harm to an unborn baby.

Contraindications

This medication cannot be used in the patients with hypersensitivity to it, breastfeeding and pregnant women.

Side effects

This medication may cause serious psychiatric symptoms which you should inform immediately to your doctor. These may include hallucinations, suicidal thoughts, severe depression, confusion, aggression, extreme fear, or unusual behavior.

Drug interaction

Sustiva decreases blood concentrations and effects of indinavir (Crixivan) and saquinavir (Invirase). Concomitant use with alcohol may increase influence of Sustiva on the central nervous system. Co-administration with Astemizol and tsizaprid increases risk of arrhythmia. Sustiva also decreases blood concentration of hormonal contraceptives and Indinavir. If Sustiva is used together with Ritonavir it leads to increase in side effects of the drug and hepatotoxicity. Concomitant use of Sustiva with Clarithromycin or Saquinavir should be avoided. Midazolam (Versed) and triazolam (Halcion) increase sedative effects of the drug. Phenobarbital decreases blood concentrations of Sustiva. Co-administration with rifabutin, rifampin is not recommended.

Do not take Sustiva with pimozide (Orap), cisapride (Propulsid), or ergot medicines such as ergotamine (Cafergot, Wigraine, Ergomar), dihydroergotamine, ergonovine (Ergotrate), or methylergonovine (Methergine).

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or time for your next dose is in a short while. Do not take double doses of this medication or extra doses of it. Take your usually dose next day in the same regularly time.

Overdose

Symptoms may include muscle twitching. In case of overdose seek urgent medical attention.

Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Symmetrel is an antiviral medication which used to prevent or treat certain influenza infections. Symmetrel blocks the actions of viruses in your body. This drug is also used for treatment Parkinson’s disease and “Parkinson-like” symptoms, including stiffness and shaking.

Dosage and direction

Take it orally with a full glass of water or food/milk. Swallow whole, do not crush it. Use Symmetrel at the same time each day for best result. The usual dosage of Symmetrel is 100 to 200 mg daily, it depends from your body weight. Also the recommended adult dose varies according to the condition being treated:

1.Treatment of Parkinson’s disease:

the recommended adult dose is 100 mg once daily to start. After one to several weeks, it may increase to 100 mg twice daily.

2.Treatment and prevention of influenza A infections:

the recommended dose for adults and children 13 years of age and older is 200 mg daily. For children 9-12 years of age, the recommended dose is 100 mg taken twice daily. For children 1 to 12 years old, the dose is prescribed by the body weight of the child.

3.To prevent influenza A infections:

Symmentrel should be taken before or after contact with a infected person and continued for 10 days after contact with him.

Note: this instruction presented here just for review. It’s very necessary to consult with your doctor before using. It help you to get best results.

Precautions

Suicide attempts and deaths have been reported in patients treated with Symmetrel. Suicide attempts and ideations have been reported in patents with and without a history of psychiatric illness. Symmetrel can exacerbate symptoms in patients with a history of psychiatric disorders or substance abuse. Patients with a history of epilepsy should be monitored closely, as well as patients with a history of congestive heart failure, peripheral edema, eczematoid rash, or renal impairment. Do not use in patients with untreated angle closure glaucoma. Patients should be closely observed upon discontinuation or dose reduction of Symmetrel, as some cases of Neuroleptic Malignant Syndrome (NMS) have been reported. NMS is a life-threatening syndrome characterized by fever, muscle rigidity, involuntary movements, altered consciousness, mental status changes and increased heart rate and blood pressure changes. Do not use alcohol during the treatment by Symmetrel. Symmetrel should not be used during pregnancy, becoming pregnant or lactating without doctor’s advice. Do not use Symmetrel before breast-feeding without doctor’s advice.

Contraindications

Symmetrel is not allowed to people who are hypersensitive to any components of this medicine. Contraindicated in case of individuals subject to convulsions or if your medical history include gastric ulceration, severe renal disease. Contraindicated in pregnancy.

Possible side effect

They may include all types of an allergic reaction. Also the most possible side effects include:

feeling short of breath, even with mild exertion;

swelling, rapid weight gain;

feeling depressed, agitated, or aggressive;

behavior changes, hallucinations, thoughts of hurting yourself;

urinating less than usual or not at all;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing, feeling like you might pass out;

restless muscle movements in your eyes, tongue, jaw, or neck; or

tremor (uncontrolled shaking).

Less serious include:

dizziness, drowsiness, headache;

sleep problems (insomnia), strange dreams;

feeling nervous;

nausea, diarrhea, constipation, loss of appetite;

dry mouth, dry nose; or

loss of balance or coordination.

If you experience one of them stop using Symmetrel and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Symmetrel interact with the following drugs: atropine; dicyclomine; glycopyrrolate; hyoscyamine; mepenzolate; methscopolamine; propantheline; scopolamine. quinine; quinidine; a diuretic such as triamterene, hydrochlorothiazide, and others; or phenothiazines such as prochlorperazine, thioridazine, and others. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.

Overdose

Deaths have been reported in patients who overdosed, so you may be more careful with taking this medication. Symptoms of Symmetrel overdose may include fever, anxiety, severe headache, confusion, hallucinations, agitation, aggression, personality changes, tremor, problems with balance or walking, fast or uneven heart rate, urinating less than usual or not at all, trouble breathing, seizure (convulsion), or fainting. If you experience one of them call your doctor immediately.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Zovirax is an antiviral medication which used to treat herpes infections of the skin, lip, and genitals; herpes zoster; and chickenpox. Zovirax stops viral replication, but it does not work in treating certain virus infections, such as the common cold.

Dosage and direction

Take it orally with or without food/milk. Commonly used dose is 200 mg every 4 hours, five times a day for ten days. If the herpes is recurrent, the recommended dose for adults is 400 mg two times a day for 1 year. Washing of your hands will help you to prevent passing the infection to others.

Note: this instruction presented here just for review. It’s very necessary to consult with your doctor before using. It help you to get best results.

Precautions

Avoid letting infected areas come into contact with other people. Do not touch your eyes after touching an infected area. Do not use without doctor’s permission if your medical history include: kidney disease or liver disease. Zovirax should not be used during pregnancy, becoming pregnant or lactating without doctor’s advice. Do not use Zovirax before breast-feeding without doctor’s advice.

Contraindications

Zovirax is not allowed in patients with kidney disorders. Also Zovirax is contraindicated in people who are hypersensitive to Zovirax, Acyclovir or similar drugs.

Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include:

pain in your lower back;

urinating less than usual or not at all;

easy bruising or bleeding;

unusual weakness.

Less serious include:

nausea, vomiting, diarrhea, loss of appetite, stomach pain;

headache, feeling light-headed;

swelling in your hands or feet.

If you experience one of them stop using Zovirax and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Zoverax interact with: probenecid (Benemid), Tizanidine, Varicella Virus Vaccine, Fosphenytoin, Phenytoin, Valproic Acid. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.

Overdose

Symptoms of Zovirax overdose include: seizure (convulsions), hallucinations, and urinating less than usual or not at all. If you experience one of them or any unusual symptom call your doctor immediately.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Valtrex is an antiviral drug which used to treat certain herpes infections, including herpes zoster (the painful rash known as shingles), genital herpes, and herpes cold sores on the face and lips. Valtrex stops viral replication and combats the herpes virus attacking it and slowing it down from replicating itself in the system allowing the body to assist in the natural defense of the spread of this virus ultimately limiting both the duration and frequency of outbreaks. Valtrex will not cure herpes, it just lessen the symptoms of the infection.

Dosage and direction

Consult with your doctor before using. Use no more than was prescribed. Take it orally with or without food every 8 hours ( 3 times a day) during one week. If you have a genital herpes take it twice daily for 5 days. For treatment of cold sores, this drug is usually taken only for one day. For best result start treatment as soon as possible after your symptoms start.

Note: this instruction presented here just for review. It’s very necessary to consult with your doctor before using. It help you to get best results.

Contraindications

Valtrex is not allowed in people with kidney disease or blood disorders. Also it is contraindicated in people who are hypersensitive to any components of this drug.

Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include:

pain in your lower back;

drowsiness, mood changes, increased thirst, loss of appetite, nausea and vomiting;

swelling, weight gain, feeling short of breath;

confusion, agitation, aggression, hallucinations, trouble concentrating;

feeling shaky or unsteady;

problems with speech or vision;

seizure (convulsions).

Less serious include:

nausea, stomach pain;

headache, dizziness, tired feeling, depression;

joint pain;

menstrual pain;

mild skin rash;

stuffy nose, sore throat.

This kinds of side effect can harm red blood cells:

fever, easy bruising or bleeding;

red spots on the skin (not related to herpes or chickenpox);

bloody diarrhea, vomiting;

pale or yellowed skin;

weakness or fainting;

urinating less than usual or not at all.

If you experience one of them stop using Valtrex and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Valtrex interact with Probenecid (Benemid) and cimetidine (Tagamet, Tagamet HB). Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.

Overdose

Symptoms of Valtrex overdose are not known. So if you experience any unusual symptom call your doctor immediately.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Famvir is an anti-viral medication which after transformation in human organism turns into penciclovir which is active against such viruses as Herpes simplex (types I and II), Varicella zoster, and the Epstein-Barr virus (EBV). Penciclovir penetrates into the cells infected by virus where being subjected to treatment by viral ferments it turns into penciclovir-triphosphate which inhibits replication of viral DNA. The medication has not effect on the non-infected cells. Famvir is active against certain strains of Herpes simplex with changed DNA polymerase which are resistant to Acyclovir (Zovirax). Famvir is administered to treat infections caused by Herpes simplex (types I and II): primal infection, aggravation of the chronic infection, prevention, shingles or chickenpox (Varicella zoster), postherpetic neuralgia, recurrent genital herpes.

Dosage and directions

Take Famvir with or without food. Take each dose with a glass of water. The recommended dose for treatment of recurrent genital herpes is 1,000 mg twice daily during one day. Recurrent cold sores should be treated by 1,500 mg taken as a single dose. To suppress recurrent genital herpes take 250 mg twice daily during 1 year. Treatment of shingles require 500 mg every eight hours for a week. In HIV-infected patients for treatment of cold sores and genital herpes 500 mg of Famvir is taken twice daily for 5-10 days. Do not take Famvir in larger amounts. Follow all recommendations of your doctor.

Precautions

Do not allow contact of the affected areas with other people. Do not touch your eyes after you touched the affected areas. Wash your hand frequently to avoid spreading of the infection to others.

Contraindications

Famvir is contraindicated in patients hypersensitive to the components of this medication, pregnant and breastfeeding women, children. Correction of the dose and certain cautiousness are needed in treatment of patients with kidney failure.

Possible side effect

The most common side effects are headache, nausea, vomiting, diarrhea, dizziness, allergic reactions. Some adult patients experience mental confusion, hallucinations. In the patients with decreased immunity pain in the stomach, fever symptoms occur.

Drug interaction

No specific interactions are known for this time.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.

Overdose

symptoms of Famvir overdose are unknown. If recommendations for treatment of the patients with kidney failure are not observed, acute kidney failure is possible. Seek for immediate medical attention if overdose is suspected.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Combivir is a combination of lamivudine (Epivir) and zidovudine (Retrovir), both components are active against the human immunodeficiency virus (HIV) and inhibit the activity of reverse transcriptase blocking the production of DNA and new viruses. Separately zidovudine and lamivudine may not be so effective as their combination which makes it more difficult for HIV to produce high resistant strains.

Dosage and direction

Adults and children under 12 years of age should take Combivir once daily. Take the drug about the same time each day to avoid missing a dose. Food does not change absorption of the medication.

Precautions

Combivir can affect the body’s acid balance. It also can be a reason to low blood cell counts (anemia). Inform your doctor if you have an existing shortage of blood cells or a disease of the bone marrow before to start treatment with Combivir. Aggravation of chronic liver disease hepatitis B is possible when treatment with Combivir is finished as its virus causative agent becomes resistant to lamivudine. Combivir sometimes causes muscle pain and inflammation, especially inflammation of the pancreas (pancreatitis). If you have abdominal pain for several days, accompanied by nausea and vomiting yo should immediately check with your doctor. Drugs for HIV may cause a redistribution of body fat: (a “buffalo hump” on the back, extra fat around the middle, and wasting in the arms, legs, and face).

Contraindications

Hypersensitivity to lamivudine or zidovudine. It cannot be used in people with low weigh (less than 110 pounds, or 50 kg). Children and patients with poor kidney or liver function who may require dose correction should not take tablets of Combivir as they contain fixed doses of amivudine or zidovudine.

Possible side effect

Serious side effects of Combivir are: decrease in blood cells, muscle breakdown, muscle pain (myopathy), liver enlargement and metabolic disturbance (lactic acidosis), allergy symptoms (rash, chills), nausea and vomiting, abdominal pain, weight loss, headache, cough and insomnia.

Drug interaction

Inform your doctor if you are takeing fluconazole (Diflucan), probenecid, trimethoprim (Trimpex) and valproic acid (Depakote). These drugs reduce the elimination of zidovudine and may lead to its increased blood concentration.

Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Overdose

Any medication taken in excessive quantities may be dangerous. Notify your doctor immediately in case of a supposed overdose and experience dizziness, drowsiness, confusion, headache, fatigue, weakness, nausea, seizure, vomiting.

Storage

Combivir should be stored at room temperature between 2-30?C (36-86 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Zoviclovir Cream 5% is an antiviral medication used to treat skin infections caused by the herpes simplex virus, including cold sores (herpes labialis) and genital herpes. It works by stopping the virus from multiplying, helping reduce the severity of symptoms and speeding up the healing process.

This cream should be applied exactly as prescribed by your doctor. Wash and dry the affected area before application. Apply a thin layer to the infected skin and surrounding area. For best results, start using Zoviclovir as soon as you notice early signs such as tingling, itching, or redness. Using it early can help prevent the sores from becoming severe. Continue using the cream for the full prescribed duration, even if symptoms start improving.

Common side effects may include mild burning, stinging, itching, dryness, or redness at the application site. These effects are usually temporary. If you notice severe irritation, swelling, or signs of an allergic reaction, stop using the cream and seek medical advice.

Zoviclovir Cream is for external use only. Avoid contact with eyes, mouth, or inside the nose. Do not use on broken or severely damaged skin unless directed by your doctor. Inform your doctor if you have a weakened immune system or if symptoms do not improve.

Uses of Zoviclovir Cream

• Treatment of cold sores (herpes labialis)

• Treatment of genital herpes

• Treatment of herpes simplex skin infections

Benefits of Zoviclovir Cream

In Herpes Infections
Zoviclovir Cream 5% helps control herpes virus activity by preventing it from multiplying. This reduces pain, itching, burning, and blister formation while promoting faster healing. Regular use as prescribed can shorten the duration of outbreaks and limit their severity.

Side Effects of Zoviclovir Cream

Most side effects are mild and go away on their own as your skin adjusts to the medicine. Consult your doctor if they persist or become bothersome.

Common side effects include:

• Burning or stinging sensation

• Itching

• Dryness

• Redness or irritation

How to Use Zoviclovir Cream

Use this medicine exactly as directed by your doctor.

• Clean and dry the affected area before application.

• Apply a thin layer of the cream to the affected skin.

• Wash your hands before and after applying the cream.

• Do not cover the area with tight bandages unless advised.

How Zoviclovir Cream Works

Zoviclovir Cream contains an antiviral agent that blocks the replication of the herpes virus. By stopping the virus from multiplying, it limits the spread of infection and helps the skin heal faster.

Safety Information

Pregnancy
Consult your doctor before using this cream during pregnancy. Use only if clearly needed.

Breastfeeding
Speak to your doctor before use. Avoid applying the cream on or near the breast area.

Driving
No known effect on driving ability.

Kidney & Liver
No known issues when used topically as directed.

Missed Application

If you forget to apply Zoviclovir Cream, use it as soon as you remember. If it is almost time for your next application, skip the missed one and continue as normal. Do not apply extra cream to make up for a missed dose.

Aciclovir is an antiviral drug, it is a synthetic ingredient with a similar molecular structure to purine nucleoside. Aciclovir is used to treat viral infections such as cold sores, to stop the growth of Herpes simplex virus, Varicella zoster virus (caused by chickenpox and shingles), Epstein Barr Virus (caused by glandular fever), and to a lesser extent Cytomegalovirus (CMV). It is also useful in preventing genital herpes and in preventing viral infections occurring in those with a lowered immune system. This medication may also help reduce how long pain remains after the sores heal. In addition, in people with a weakened immune system, Aciclovir can decrease the risk of the virus spreading to other parts of the body and causing serious infections.

Dosage and direction

Take this medication by mouth with or without food, usually 2 to 5 times a day as directed by your doctor. Take this medicine by mouth with a glass of water. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think your are better. If you are using the liquid form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Dosage is based on your medical condition and response to treatment. In children, dosage is also based on weight.

Precautions

You should talk with your healthcare provider prior to taking Aciclovir if you have kidney disease, including kidney failure (renal failure), any allergies, including allergies to food, dyes, or preservatives. Let your healthcare provider know if you are pregnant or thinking of becoming pregnant, breastfeeding.

Make sure to tell your healthcare provider about all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

The medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug

Contraindications

Aciclovir Injection is contraindicated for patients who develop hypersensitivity to aciclovir or valaciclovir.

Possible side effects

Side effects are potentially serious and you should report to your doctor or health care professional as soon as possible. These include, but are not limited to: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue, chest pain, confusion, hallucinations, tremor, dark urine, increased sensitivity to the sun, redness, blistering, peeling or loosening of the skin, including inside the mouth, seizures, trouble passing urine or change in the amount of urine, unusual bleeding or bruising, or pinpoint red spots on the skin, unusually weak or tired, yellowing of the eyes or skin. Side effects that usually do not require medical attention: diarrhea, fever, headache, nausea, vomiting stomach upset. In this way report to your doctor or health care professional if they continue or are bothersome.

Drug interactions

There are negative interactions that can occur when Aciclovir is combined with any of the drugs listed above. Phenytoin (Fosphenytoin) and Aciclovir: it may decrease the level of phenytoin in your blood, perhaps making it less effective. Your healthcare provider may need to measure the level of phenytoin in your blood (using a blood test) and adjust your dose as necessary. Probenecid can increase the level of Aciclovir in your blood, increasing your risk of acyclovir side effects. Your healthcare provider may need to decrease your acyclovir dosage to prevent this interaction from occurring. Acyclovir can increase the level of Tenofovir in your blood, potentially increasing your risk of side effects. Your healthcare provider may need to lower your tenofovir dosage to prevent drug interactions from occurring.

Missed dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include seizure (convulsions), hallucinations, and urinating less than usual or not at all.

Storage

Store at controlled room temperature of 15°C to 25°C (59°F to 77°F). Keep this medicine out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.