Ovral contains ethinyl estradiol and norgestrel, female hormones used to prevent ovulation as a contraception medication. The drug changes condition of cervical mucus and uterine lining and hampers movement of sperm cells to the uterus and attachment of a fertilized egg to the uterus.

Dosage and direction

Follow all recommendations of your health care advisor. Take the first on the first day of your menses or on the first Sunday after your period started. If you use Ovral for the firs time you may need additional birth control means. There are 28-day birth control packs with seven ‘reminder’ pills for the regular cycle. While you are using ‘reminder’ pills the period usually begins. Breakthrough bleeding is possible, if it becomes heavy and continues, inform your doctor. Take each pill each day about the same time. When your pill pack is over start a new one. In case of needed medical tests or surgery, it is possible that you may need to stop using Ovral for a short period of time.

Precautions

Additional birth control methods (condoms or a spermicide) may be needed when you start to use Ovral.

Intake of hormones may increase the risk of blood clotting, heart attack, stroke, especially in the patients over 35 y.o. or smokers. Inform your doctor if you have problems with heart, blood pressure, congestive heart failure, angina, high cholesterol, depression in history, seizures or epilepsy, diabetes, gallbladder disease, varicose veins, tuberculosis, uterine fibroid tumors, a history of fibrocystic breast disease, nodules, lumps.

Contraindications

This medication cannot be used in pregnant women or those just after delivery, in patients with a stroke or blood clot in history, circulation problems, vaginal bleeding, hormone-related cancer, liver disease or liver cancer, circulation problems, abnormal vaginal bleeding, migraine headaches, a heart valve disorder, severe high blood pressure, jaundice caused by birth control pills in history.

Side effects

Besides allergic symptoms (hives, skin rash, facial swelling, difficulty breathing) this medication may be a reason of sudden numbness or weakness, pain behind the eyes, problems with vision, headache, confusion, speech, or balance, a change in the pattern or severity of migraine headaches, chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling, swelling of the extremities, depression, loss of appetite, nausea, stomach pain, dark urine, jaundice.

Drug interaction

There are drugs which can interact with Ovral. Inform your doctor about all prescribed and over-the counter medications, herbal products and food supplements you use and especially about theophylline (Respbid, Theo-Dur), acetaminophen (Tylenol) or ascorbic acid (vitamin C), prednisolone (Orapred), St. John’s wort, seizure medications, cyclosporine (Gengraf, Neoral, Sandimmune), a barbiturate sedatives, HIV or AIDS medications, and antibiotics.

Missed dose

If you missed a pill risk of becoming pregnant increases. If you forgot to take one ‘active’ pill, take two pills as soon as you remember then return to your schedule. If you miss two ‘active’ pills in a row in first or second week of treatment, take two pills a day for two days in a row. Then return to your schedule. Use birth control test during seven days if such a ‘mistake’ occurred. If you miss two ‘active’ pills in a row during third week, or if you miss three pills in a row during any of the first three weeks, you need to start a new pack of pills as if you are a First Day starter.

If you did not take three ‘active’ pills in a row during any of the first three weeks, start a new pack on the same day as if you are a First Day starter.

If you skipped intake of two or more pills, you may not have a monthlies during this month. If you miss a period for two months in a row you might be pregnant.

If you miss any reminder pills, throw the missed pills away and return to your schedule.

Overdose

The most expected overdose symptoms of this medication are vomiting, nausea, and vaginal bleeding.

Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.

Parlodel is a stimulator of the central and peripheral D2-dopamine receptors (a derivative of ergot alkaloids). It inhibits a secretion of prolactin, suppresses the physiological lactation, promotes normalization of periods, inhibits an excessive secretion of growth hormone, reduces size and number of cysts in the breast (normalizing the imbalance between progesterone and estrogen). Its high doses stimulate dopamine receptors in the striatum, the substantia nigra in brain, hypothalamus and mesolimbic system. Parlodel is used to treat infertility in some women, abnormal stoppage or absence of flow in periods, growth hormone overproduction leading to acromegaly, Parkinson’s disease, pituitary gland tumors.

Dosage and direction

Take this medication when you are in a lying position and do not rise up quickly after the intake. Do not stop to take this drug even if your symptoms do not change and it seems that no result is achieved. Parlodel may require longterm treatment before its effect is manifestated.

Precautions

In case of a severe headache which does not stop but only worsens, and if experience including seizure, stroke, or heart attack after taking Parlodel contact your doctor. If you became pregnant using this drug inform your doctor immediately about it. Also notify your doctor if you have liver or kidney disease, hypertension, circulation problems or heart attack in history before to use Parlodel. Cautiousness should be exercised in patients with mental problems, any disease of the heart and circulatory system, peptic ulcer, or bleeding in the stomach and intestines. This medication affects ability to drive a car or operate machinery.

Contraindications

Hypersensitivity, gestosis, arterial hypertension after delivery of a baby, essential tremors and familial tremor, Huntington’s disease, cardiovascular diseases, endogenous psychosis, hypertension, hypotension, liver failure, ulcerative lesions of gastrointestinal tract. Cautiously should be exercised in patients with Parkinson disease (including signs of dementia), pregnancy, simultaneous treatment for hypertension.

Possible side effect

Parlodel usually does not have any side effects but if any appear consult your doctor as you may need immediate medical help. These are symptoms you should be very attentive to while taking Parlodel: Abdominal cramps or discomfort, confusion, constipation, depression, diarrhea, dizziness, drop in blood pressure, drowsiness, dry mouth, a persistent watery nasal discharge, hallucinations (particularly in Parkinson’s patients), headache, inability to sleep, indigestion, light-headedness, loss of coordination, nausea.

Drug interaction

Alcohol beverages may worsen side effects of Parlodel (tachycardia, chest pain, nausea). Inform your doctor if you are taking blood pressure-lowering drugs (Aldomet and Catapres), Metoclopramide (Reglan), oral contraceptives, any ergot derivatives (Hydergine, Pimozide). Effectiveness of oral contraceptives may be decreased if they are taken with Parlodel.

Missed dose

Take it as soon as you remember but not if it is more than 4 hours since the time of intake you missed. If you remembered about the missed dose after 4 hours and more since the time you missed it, just skip this intake and return to your regular schedule. Do not double dose this medication.

Overdose

If you suspect that you took too much of the medication seek for immediate medical attention and drink glass of milk. Possible overdose symptoms include pale skin, sweating, and repetitive yawning.

Storage

Store Parlodel in a dry tight container away from sunlight at room temperature between 15-30 C (59-86 F) away from children and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Mircette is a combination of female hormones such as desogestrel/ethinyl estradiol and ethinyl estradiol used to prevent ovulation. This contraception medication changes condition of cervical mucus and uterine lining and hampers movement of sperm cells to the uterus and attachment of a fertilized egg to the uterus.

Dosage and direction

Follow all recommendations of your health care advisor. Take the first on the first day of your menses or on the first Sunday after your period started. If you use Mircette for the firs time you may need additional birth control means. There are 28-day birth control packs with seven ‘reminder’ pills for the regular cycle. While you are using ‘reminder’ pills the period usually begins. Breakthrough bleeding is possible, if it becomes heavy and continues, inform your doctor. Take each pill each day about the same time. When your pill pack is over start a new one. In case of needed medical tests or surgery, it is possible that you may need to stop using Mircette for a short period of time.

Precautions

Additional birth control methods (condoms or a spermicide) may be needed when you start to use Mircette.

Intake of hormones may increase the risk of blood clotting, heart attack, stroke, especially in the patients over 35 y.o. or smokers. Inform your doctor if you have problems with heart, blood pressure, congestive heart failure, angina, high cholesterol, depression in history, seizures or epilepsy, diabetes, gallbladder disease, varicose veins, tuberculosis, uterine fibroid tumors, a history of fibrocystic breast disease, nodules, lumps.

Contraindications

This medication cannot be used in pregnant women or those just after delivery, in patients with a stroke or blood clot in history, circulation problems, vaginal bleeding, hormone-related cancer, liver disease or liver cancer, circulation problems, abnormal vaginal bleeding, migraine headaches, a heart valve disorder, severe high blood pressure, jaundice caused by birth control pills in history.

Side effects

Besides allergic symptoms (hives, skin rash, facial swelling, difficulty breathing) this medication may be a reason of sudden numbness or weakness, pain behind the eyes, problems with vision, headache, confusion, speech, or balance, a change in the pattern or severity of migraine headaches, chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling, swelling of the extremities, depression, loss of appetite, nausea, stomach pain, dark urine, jaundice.

Drug interaction

There are drugs which can interact with Mircette. Inform your doctor about all prescribed and over-the counter medications, herbal products and food supplements you use and especially about theophylline (Respbid, Theo-Dur), acetaminophen (Tylenol) or ascorbic acid (vitamin C), prednisolone (Orapred), St. John’s wort, seizure medications, cyclosporine (Gengraf, Neoral, Sandimmune), a barbiturate sedatives, HIV or AIDS medications, and antibiotics.

Missed dose

If you missed a pill risk of becoming pregnant increases. If you forgot to take one ‘active’ pill, take two pills as soon as you remember then return to your schedule. If you miss two ‘active’ pills in a row in first or second week of treatment, take two pills a day for two days in a row. Then return to your schedule. Use birth control test during seven days if such a ‘mistake’ occurred. If you miss two ‘active’ pills in a row during third week, or if you miss three pills in a row during any of the first three weeks, you need to start a new pack of pills as if you are a First Day starter.

If you did not take three ‘active’ pills in a row during any of the first three weeks, start a new pack on the same day as if you are a First Day starter.

If you skipped intake of two or more pills, you may not have a monthlies during this month. If you miss a period for two months in a row you might be pregnant.

If you miss any reminder pills, throw the missed pills away and return to your schedule.

Overdose

The most expected overdose symptoms of this medication are vomiting, nausea, and vaginal bleeding.

Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Serophene is an non-steroid anti-estrogen. Mechanism of its action consists in a specific binding with receptor for estrogen in ovary and hypophis. In patients with low estrogen levels in organism it causes estrogen effect and in ones with high estrogen levels it causes anti-estrogen effect. Its small doses increase secretion of gonadotropins (prolactin, Follicle stimulating hormone, FSH and interstitial cell-stimulating hormone), stimulates ovulation; in large doses slows secretion of gonadotropins. In the whole action of Serophene consists in stimulation of ovulation to occur and prepares the body for pregnancy. This medication may be used for male patients with infertility caused by low production of sperm.

Dosage and direction

Serophene is administered to stimulate ovulation 50 mg 1 time a day at bedtime, starting from 5th day of the menstrual cycle during 5 days (in the absence of the cycle – at any time). In case of no effect (ovulation does not occur within 30 days) increase the dose to 150 mg / day or lengthen the course to 10 days. Take exactly as prescribed, do not take the medication in larger quantities.

Precautions

Before to take Serophene notify your doctor if you have ever had any allergic reaction to clomiphene, liver diseases, mental depression, thrombophlebitis. This drug may cause vision problems, dizziness, or lightheadedness, be especially attentive if you need driving or operating machinery which requires high concentration of attention.

Contraindications

Hypersensitivity, liver or kidney failure, metrorrhagia of unknown etiology, ovarian cysts, neoplasms of genital organs, tumor or hypofunction of the hypophysis, endometriosis, ovarian failure together with hyperprolactinaemia, pregnancy.

Possible side effect

Together with allergy symptoms such as swelling of lips, tongue, or face or hives in some patients may appear the following conditions: ovarian enlargement presenting as abdominal or pelvic pain, flushing, nausea, vomiting, or diarrhea, blurred vision, headache, abnormal uterine bleeding.

Drug interaction

Inform your doctor and laboratory operators about all medications and herbal products you are taking if you are treated with Serophene.

Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If so skip the missed dose. Do not try to make up a missed dose by taking an extra one.

Overdose

If you suspect that you took too much of the medication seek for immediate medical attention.

Storage

Store Serophene in a dry place away from sunlight at room temperature between 15-30 C (59-86 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. The specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

This medicine works by regulating the growth and shedding of the uterine lining, thereby helping to control menstrual flow and reduce pain and discomfort. Norlut-N Tablet may be taken with or without food, preferably at the same time each day, as advised by your doctor. The dosage and duration depend on the condition being treated and your individual response to therapy.

Some common side effects include headache, nausea, abdominal pain, vaginal spotting, hair loss, and breast tenderness. These are usually mild and temporary. However, you should stop taking the medicine and seek medical advice immediately if you develop symptoms such as jaundice, migraine, visual disturbances, sensory changes, high blood pressure, or if you become pregnant.

Uses of Norlut-N Tablet

• Treatment of Premenstrual Syndrome (PMS)

• Treatment of Painful Menstruation (Dysmenorrhea)

• Treatment of Heavy Menstrual Bleeding

• Treatment of Endometriosis

Benefits of Norlut-N Tablet

In Premenstrual Syndrome (PMS)

Norlut-N Tablet helps manage PMS symptoms such as mood swings, bloating, breast tenderness, headaches, and fatigue by stabilizing hormonal fluctuations. When combined with lifestyle changes like regular exercise, a balanced diet, and proper rest, it can significantly improve quality of life.

In Menstrual Disorders & Endometriosis

It helps regulate menstrual cycles, reduce excessive bleeding, relieve pain, and control abnormal growth of uterine tissue in endometriosis.

Side Effects of Norlut-N Tablet

Most side effects are mild and usually resolve as your body adjusts to the medicine. Consult your doctor if they persist or worsen.

Common Side Effects:

• Headache

• Nausea or vomiting

• Abdominal cramps or pain

• Vaginal spotting

• Hair loss

• Breast tenderness

How to Use Norlut-N Tablet

Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with water. Do not chew, crush, or break it. It may be taken with or without food.

How Norlut-N Tablet Works

Norlut-N Tablet is a synthetic progestin that mimics the effects of natural progesterone. It regulates the growth and shedding of the uterine lining, helping manage menstrual irregularities, heavy bleeding, and hormone-related conditions.

Safety Advice

Alcohol: Consult your doctor
Pregnancy: Unsafe – may cause serious harm to the unborn baby
Breastfeeding: Unsafe – may harm the baby
Driving: Unsafe – may cause dizziness or visual disturbances
Kidney: Consult your doctor
Liver: Unsafe – contraindicated in liver disease

Important:

• Stop the medicine and consult your doctor if you develop jaundice, migraine, or sensory changes

• Inform your doctor about diabetes, migraines, blood circulation problems, or all other medicines you are taking

• This medicine may affect some blood and urine test results

Missed Dose

If you miss a dose of Norlut-N Tablet, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Premarin is a mixture of estrogen hormones which regulates development and functions of female reproductive system, formation of female secondary characteristics. On entering into the bloodstream it forms a complex with a specific receptor (in the fallopian tubes, cervix, excretory ducts of the mammary glands, vagina, urethra, breast, liver, hypothalamus, hypophisis), stimulates synthesis of DNA and proteins. It results in proliferation of the epithelium, increased sensitivity of the uterus and tubes muscles of to medications stimulatign their motility. This medication decreases bone resorption of Ca2 + in menopause, prevents involution of the genitals. Premarin is used to treat symptoms of menopause which include hot flashes, vaginal dryness, vaginal irritation and dryness, to prevent osteoporosis in postmenopausal women. Replacement therapy in peri- and postmenopausal women, ovarian hypofunction (primary and secondary amenorrhea, oligomenorrhea, dysmenorrhea) and other conditions.

Dosage and direction

Take this medication once daily as prescribed with a full glass of water with or without food. Premarin may be administered for a cyclic treatment which consists of 25 days on followed by 5 days. Do not take in larger amounts than prescribed. Individual dosage depends on your condition (for hypogonadism 0.3 mg or 0.625 mg daily, for preventing postmenopausal osteoporosis is 0.3 mg/day). Try your best to take it regularly to get the best benefit from it. Do not take with grapefruit juice, it increases levels of estrogen.

Precautions

Long-term treatment with Premarin may increase risk of breast cancer, endometrial hyperplasia, heart attack, or stroke so monitoring of the patient’s state should be done on a regular basis. This medication can be harmful to an unborn baby, do not use it during pregnancy. Do not use Premarin to prevent hart disease or dementia. To avoid endometrial hyperplasia you may be prescribed to take a progestin together with Premarin. Do not use this drug if you are under 18 y.o..

Contraindication

Hypersensitivity, pregnancy, breastfeeding, estrogen depending malignant tumors, undiagnosed genital or uterine bleeding, thrombophlebitis or thromboembolic disease in active phase (excluding treatment of breast and prostate cancers). Cautiousness should be exercised in patients with thrombophlebitis, thrombosis or thromboembolism (while taking estrogens in history); family hyperlipoproteinemia, pancreatitis, endometriosis, gallbladder disease in history (especially cholelithiasis), severe liver failure, jaundice (including one during pregnancy in history), hepatic porphyria, leiomyoma, hypercalcemia associated with bone metastases caused by breast cancer, underactive thyroid, porphyria, endometriosis, asthma.

Possible side effect

You may experience symptoms of allergy (hives, rash, swelling face and tongue) and also chest pain or heavy feeling, sudden numbness or weakness, abnormal vaginal bleeding, migraine headache, confusion, jaundice, swelling in hands, ankles, or feet. If such symptoms are severe stop taking this medication and notify your doctor at once.

Drug interaction

Estrogens stimulate the liver’s ability to produce factors that promote the clotting of blood. Thus, concomitant administration of Premarin and warfarin (blood thinner) may cause decrease their effects. Barbiturates, Rifampin (Rifadin), phenytoin (Dilantin), carbamazepine (Tegretol), griseofulvin (Grifulvin), St. John’s wort and primidone increase metabolism of estrogens. Erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), and ritonavir (Norvir) act oppositely.

Missed dose

Take the missed dose as soon as you remember about it. If it is almost time of your next dose just skip it and return to your regular schedule.

Overdose

Immediate medical attention in needed in case you overdosed intake of the medicine. Symptoms may include vomiting, nausea, and vaginal bleeding.

Storage

Premarin should be stored at room temperature, between 15-30 C (59-86 F). The right temperature to store the injection is between 2-8 C (36-46 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Dostinex is a synthetic ergoline with a high affinity to dopamine D2 receptors, a strong prolonged activity inhibitor of prolactin secretion. Prolactin is a hormone that is released from the hypophysis. This medication is used to treat hormonal imbalance with much prolactin in the blood (hyperprolactinemia) to reduce or prevent breast milk production, except after childbirth (postpartum).

Dosage and direction

Take this medication exactly as prescribed by your doctor. Take it orally twice weekly. Dostinex is usually taken twice each week for at least 6 months. Dosage is adjusted generally at 4 week periods based on tests for prolactin levels in blood.

Precautions

Avoid drinking alcoholic beverages. Before to take Dostinex notify your doctor about allergies, liver diseases, psychiatric illnesses, uncontrolled high blood pressure, high blood pressure during pregnancy which you may suffer or if you are breastfeeding . Get up slowly from a sitting or a lying position to avoid dizziness or lightheadedness caused by this medication.

Contraindications

Dostinex is contraindicated in patients with uncontrolled hypertension or known hypersensitivity to ergot derivatives (ergotamine, ergonovine, Ergomar, Cafergot, dihydroergotamine, Migranal Nasal Spray, D.H.E. 45, Ergotrate, or methylergonovine, Methergine, pulmonary, pericardial, cardiac valvular, or retroperitoneal fibrotic disorders in history.

Possible side effect

Side effects may include symptoms of allergy (hives, rash, swelling of face and tongue, acne). Major side effects are: cough or trouble breathing, feeling light-headed, fainting, nausea, vomiting, stomach pain, constipation, headache, numbness. Contact your doctor if you experience severe symptoms listed above as you might need immediate medical help.

Drug interaction

Inform your doctor about all medications or herbal products you take, especially about: blood pressure drugs, dopamine blockers (metoclopramide, antipsychotics such as chlorpromazine, haloperidol); drugs that cause drowsiness, sedatives, sleeping pills, narcotic pain relievers (codeine), anti-anxiety medications, antidepressants, muscle relaxants, anti-seizure medications, certain antihistamines (diphenhydramine). Never take this drug without your doctor’s approval.

Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If so skip the missed dose. Do not try to make up a missed dose by taking an extra one.

Overdose

If you suspect that you took too much of the medication seek for immediate medical attention. Your symptoms may appear as mental changes, nasal congestion, fainting, lightheadedness, or irregular heartbeat.

Storage

Store Dostinex in a dry tight container away from sunlight at room temperature between 15-30 C (59-86 F) away from children and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Levonorgestrel is a hormone used as a contraception medication it is similar to progesterone and is its racemic isomer (norgestrel), which is twice more potent. The drug changes condition of cervical mucus and uterine lining and hampers movement of sperm cells to the uterus and attachment of a fertilized egg to the uterus. Levonorgestrel is administered to prevent pregnancy within 72 hours after the intercourse, if no contraceptive methods were used during it, or the used method was not reliable.

Dosage and direction

Take the medication orally. Take two tablets this way: the first tablet is taken as soon as possible after the intercourse (not later than within 72 hours); the second tablet should be taken in 12 hours (but not later than 16 hours) after the first tablet. If you had vomiting within three hours after intake of any tablet, take one more tablet. Levonorgestrel tablet of 0.75 mg may be taken on any day of your menses only if your previous period was normal. After emergency treatment with Levonorgestrel local barrier methods of contraception should be used (e.g. a condom).

Precautions

Recurrent use of Levonorgestrel during one menstrual cycle is not recommended due to possible disorders of the period. The medication does not substitute regular contraception medication and should be used only in case of emergency. Emergency medication sometimes fails to prevent pregnancy. This medication excretes to the breast milk. Take the pills after breastfeeding to decrease negative effects on your baby and avoid breastfeeding after the treatment. Inform your doctor if you have a bleeding or blood-clotting disorder, diabetes, a vaginal infection.

Contraindications

Do not take Levonorgestrel if you are pregnant because the medication does not end the pregnancy which has already occurred. The medication cannot be used in patients with abnormal vaginal bleeding, untreated or uncontrolled pelvic infection, serious pelvic infection following a pregnancy or abortion within the past 3 months, uterine fibroid tumors, history of pelvic inflammatory disease (PID), past or present breast cancer, liver disease or liver tumor, cervical or uterine cancer; a recent abnormal Pap smear, decreased immunity (leukemia, AIDS, IV drug abuse).

Side effects

The most frequent adverse reactions of Levonorgestrel include nausea, irregular pap smear bleeding, delay of menses for more than 7 days, dizziness, headache, a pain in the lower abdomen, nausea, vomiting, tension of the mammary glands, fatigue.

Drug interaction

Simultaneous use of the drugs, which induce liver enzymes accelerates metabolism of Levonorgestrel. These drugs may reduce the effectiveness of Levonorgestrel: barbiturates, including primidon, phenytoin and carbamazepine and drugs that contain St. John’s wort (Hypericum perforatum), rifampicin, ritonavir, rifabutin, griseofulvin. Drugs that contain Levonorgestrel may increase toxicity of cyclosporine.

Missed dose

Missed dose is not supposed as this medication is taken when needed.

Overdose

Vomiting and bleeding are possible. Contact your doctor if you suspect overdose.

Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Provera contains medroxyprogesterone acetate, female hormone used to regulate ovulation and menstrual periods. The medication is used to treat secondary amenorrhea and abnormal uterine bleeding caused by hormonal imbalance (fibroids, uterine cancer), to reduce the incidence of endometrial hyperplasia in postmenopausal women.

Dosage and direction

Take 5 or 10 mg of this medication daily for 5 to 10 days. Take exactly according to recommendations of your doctor. Avoid taking larger amounts of the medication. Your doctor may administer to start taking the medication on a certain day of your menses. While you are on Provera examine your breasts for lumps on a monthly basis. Provera may change results of certain medical tests. Inform your doctor that you take this drug.

Precautions

Do not smoke while you take Provera, unless risk of blood clotting increases. Inform your doctor about conditions you may have as dose adjustment may be needed: hypertension, heart disease, recent stroke or heart attack, congestive heart failure, hypercalcinemia, high cholesterol or triglycerides, recent miscarriage or abortion, severe pelvic pain, asthma, migraine headaches, epilepsy, a thyroid disorder, diabetes, kidney disease, lupus, depression.

Contraindications

Do not take this medication if you have hypersensitivity to its components, pregnant, suffer with a hormone-related cancer of genitals or mammary gland, abnormal vaginal bleeding that has not been diagnosed, have liver disease, a history of stroke or blood clot, or breastfeed.

Side effects

The most frequent side effects of Provera are headache, dizziness, irritability, insomnia, drowsiness, fatigue, depression, nausea, abdominal pain, thrombophlebitis, cerebrovascular disorders, hypersensitivity nipple breast, galactorrhoea, erosion of the cervix, dysmenorrhea. High doses of the medication may produce acne, hirsutism, changes in body weight, moon face, hyperthermia, alopecia. Allergic reactions such as hives, rash, facial swelling and difficulty breathing are also possible.

Drug interaction

Aminoglutethimide reduces plasma concentrations and reduces efficiency of Provera. Inform your doctor about all prescribed and over-the-counter medications, herbal products, vitamins and food supplements you use.

Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Overdose

Overdose symptoms may be: dizziness, drowsiness, stomach pain, nausea, vomiting, breast tenderness, or vaginal bleeding. Seek immediate medical help if you experience the symptoms listed above.

Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Yasmin contains Drospirenone (a synthetic hormone progestin)and Ethinyl Estradiol and is used as a preventive drug to avoid pregnancy. It interferes with woman menstrual cycle and tricks the body as if ovulation has taken place even if it has not. So a ripened egg is not released by the ovaries. The drug changes condition of cervical mucus and uterine lining and hampers movement of sperm cells to the uterus and attachment of a fertilized egg to the uterus.

Dosage and direction

Start treatment on the very first day of your menstrual cycle and then take one pill daily. If you missed a daily dose take taking two pills as a single dose. Risk of your pregnancy increases if you miss more than one dose. Do not take other contraceptive pill concomitantly with Yasmin to avoid serious hormonal imbalance. Each pill contains 3.0 mg of drospirenone and 0.030 mg of ethinyl estradiol, while 7 ‘inactive’ pills do not contain the hormones.

Precautions

Additional birth control methods (condoms or a spermicide) may be needed when you start to use Yasmin.

Intake of hormones may increase the risk of blood clotting, heart attack, stroke, especially in the patients over 35 y.o. or smokers. Inform your doctor if you have problems with heart, blood pressure, congestive heart failure, angina, high cholesterol, depression in history, seizures or epilepsy, diabetes, gallbladder disease, varicose veins, tuberculosis, uterine fibroid tumors, a history of fibrocystic breast disease, nodules, lumps.

Contraindications

You should not use this medication in patients with hypersensitivity to the medication, undiagnosed abnormal genital bleeding, breast cancer (known, suspected, or in history), known or suspected estrogen-dependent neoplasia, blood clots, myocardial infarction, pregnancy, breastfeeding, problems with liver, plague. The medication cannot be used in the girls who have not yet had their first menstrual period.

Possible side effect

Yasmin may increase potassium levels in some individuals, thus, women with kidney disease, liver bug, or adrenal disease should not be treated by it. Also some women may develop nausea, vomiting, weight gain, headaches, palpitations, fainting or dizziness, breast tenderness and enlargement, changes in the menstrual cycle, vaginal thrush, water retention in the body. More serious but rare adverse reactions include increase in blood pressure, depression, liver disorders and blood clots in vessels.

Drug interaction

There are drugs which can interact with Yasmin. Inform your doctor about all prescribed and over-the counter medications, herbal products and food supplements you use and especially about theophylline (Respbid, Theo-Dur), acetaminophen (Tylenol) or ascorbic acid (vitamin C), prednisolone (Orapred), St. John’s wort, seizure medications, cyclosporine (Gengraf, Neoral, Sandimmune), a barbiturate sedatives, HIV or AIDS medications, and antibiotics.

Missed dose

If you missed a pill risk of becoming pregnant increases. If you forgot to take one ‘active’ pill, take two pills as soon as you remember then return to your schedule. If you miss two ‘active’ pills in a row in first or second week of treatment, take two pills a day for two days in a row. Then return to your schedule. Use birth control test during seven days if such a ‘mistake’ occurred. If you miss two ‘active’ pills in a row during third week, or if you miss three pills in a row during any of the first three weeks, you need to start a new pack of pills as if you are a First Day starter.

If you did not take three ‘active’ pills in a row during any of the first three weeks, start a new pack on the same day as if you are a First Day starter.

If you skipped intake of two or more pills, you may not have a monthlies during this month. If you miss a period for two months in a row you might be pregnant.

If you miss any reminder pills, throw the missed pills away and return to your schedule.

Overdose

Signs of overdose include nausea and vomiting, vaginal bleeding, increased level of blood potassium. If you suspect overdose contact your health care provider the soonest or seek immediate medical attention.

Storage

Store at room temperature, below 25 C (77 F) and out of reach and children and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.