Lopid is similar to fenofibrate (Tricor) and a fibric acid derivative. It acts reducing triglycerides and increasing cholesterol carried in high density lipoprotein thus decreasing risk of atherosclerosis, stroke, heart attack. Mechanism of its action is not known. Lopid is especially good in treatment of high cholesterol and triglyceride levels in patients with pancreatitis.

Dosage and direction

The recommended dose is 600 mg 30 minutes taken twice daily: before breakfast and dinner.

Precautions

Follow all instructions of your doctor about diet, exercise routine, and weigh control mechanisms, as this medication is only a part of the treatment. Avoid consumption of food which is rich with cholesterol or fats. Regular monitoring of your blood fat is needed on a regular basis. Your doctor may demand regular examination of your kidney or liver function. Inform your doctor if you have liver disease, gallbladder disease, severe kidney disease.

Contraindications

Lopid is contraindicated in individuals with allergic reaction to gemfibrozil, liver disease, gallbladder disease, severe kidney disease, or when co-administered with repaglinide (Prandin).

Possible side effect

Immediate medical help is required if you feel sharp pain in your upper stomach after the intake of Lopid or eating, jaundice, blurred vision, painful urination, eye pain, seeing halos around lights.

Drug interaction

Risk of rhabdomyolysis (muscle injury) increases when gemfibrozil is used with the statin family of cholesterol-reducing medications: pravastatin (Pravachol), lovastatin (Mevacor), rosuvastatin (Crestor), simvastatin (Zocor), fluvastatin (Lescol), and atorvastatin (Lipitor). When this condition is severe it may result in serious kidney damage and death. Concomitant use of these medications is not recommended, symptoms of rhabdomyolysis may appear in three weeks or several months after co-administration. Concomitant use with warfarin increases bleeding and requires correction of warfarin doses. Blood levels of repaglinide (Prandin) are increased by Lopid in patients with diabetes.

Cholestyramine (Questran) and Colestipol (Colestid) reduce effects of Lopid when co-administered. Lopid should be administered an hour before or 4-6 hours after intake of cholestyramine or colestipol.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended doses. Take your usually dose next day in the same regularly time.

Overdose

Symptoms of overdose are: nausea, diarrhea, vomiting, stomach cramps, joint or muscle pain. Seek immediate medical attention if you experience these symptoms.

Storage

Store at room temperature between 20-25 C (68-77 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Tricor contains active substance fenofibrate. In the tissues it turns into the active metabolite: fenofibric acid. Together with a diet it is used to treat people with very high levels of triglycerides in the blood or lipid disorders. The drug increases activity of lipoprotein lipase, catabolism of triglycerides in the very low density lipoproteins (VLDL), accelerates transfer of cholesterol from atherogenic the very low density lipoproteins (VLDL) to the antiatherogenic high-density lipoproteins (HDL), decreases synthesis of VLDL.

Dosage and direction

Take orally 160 mg of Tricor three times a day as initial dose to treat high cholesterol levels or a combination of high cholesterol and high triglycerides. For treatment of high triglyceride levels

the starting dose of Tricor is 54-160 mg a day. It may be gradually increased every 4-8 weeks up to maximal dose of Tricor 160 mg a day if triglycerides do not improve.

Precautions

Activity of transaminases should be monitored on a regular basis in the patients taking Tricor. If blood tests for ALT increase 2 and more times and accompaigned by myalgia and muscle weakness, treatment with Tricor should be discontinued. Tricor treatment combined with a hypolipidemic diet should be exercised only under control of a doctor and and continue for a long period of time. Tricor has the potential to cause gallstones.

Contraindications

Hypersensitivity to the components of Tricor.

Possible side effect

Cholelithiasis, increased levels of transaminases and creatine kinase, nausea, vomiting, diarrhea, myalgia, myositis, rhabdomyolysis (is the rapid breakdown of skeletal muscle due to injury to muscle tissue), acute renal failure, dizziness, headache, abdominal pain, back pain, fatigue, impotence, skin rash. If you experience these symptoms contact your doctor immediately.

Drug interaction

Inform your doctor about all prescribed and over-the-counter medication you are currently taking and especially about “blood thinners” (warfarin), cyclosporine (cholesterl-lowering drug), MAO inhibitors (selegiline, furazolidone, tranylcypromine, phenelzine, moclobemide), diabetic medicine (glipizide, insulin), estrogens/birth control pills, “statins” (lovastatin, pravastatin, simvastatin, atorvastatin) and high-dose niacin (1 gram or more per day). Combined with Tricor the two last types of drugs may cause muscle injury (myopathy).

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.

Overdose

Any drug taken in excess may be dangerous. If you suspect an overdose, seek immediate medical help.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Zetia is an antihyperlipidemic agent which used for treating high blood cholesterol along with a low-fat, low-cholesterol diet. Also it is used to treat high blood sitosterol and campesterol along with diet therapy. Heart disease or heart attacks arent prevented by Zetia as tests show.

Dosage and direction

Take this medication orally with or without food/milk. The recommended Zetia dose is 10 mg once daily. Patients who require a larger reduction in LDL-C (over 55%) may be started at 10-40 mg once daily.

Note: this instruction presented here just for review. It’s very necessary to consult with your doctor before using. It help you to get best results.

Precautions

Do not use it without doctor permission. Be careful if you have specific medical conditions then this medicine should not be taken along with statins. This is especially true if you have liver disease or are pregnant or intend to get pregnant. If you are pregnant this drug should only be taken if it is absolutely necessary. If you drink large quantities of alcohol you should be closely monitored by their doctor while they are taking this medication.

Contraindications

Not allowed in people who are hypersensitivity to any component of this medication. The combination of Zetia with an HMG-CoA reductase inhibitor is not allowed in patients with active liver disease or unexplained persistent elevations in serum transaminases. All HMG-CoA reductase inhibitors are not allowed in pregnant and nursing women. Myopathy and rhabdomyolysis.

Possible side effect

They may include all types of an allergic reactions. Also the most possible side effects include:

unusual muscle weakness, tenderness, or pain;

loss of appetite, nausea, clay-colored stools, stomach pain, low fever, dark urine, jaundice;

chest pain;

pancreatitis;

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.

Less serious include:

numbness or tingly feeling;

mild stomach pain, diarrhea;

tired feeling;

headache;

dizziness;

depressed mood;

runny or stuffy nose, cold symptoms;

joint pain, back pain; or

cough.

If you experience one of them stop using Zetia and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Zetia interact with the following medications: cholestyramine (Prevalite, Questran); colestipol (Colestid); colesevelam (Welchol); gemfibrozil (Lopid); cyclosporine (Neoral, Sandimmune, Gengraf); or a blood thinner such as warfarin (Coumadin).

Also note that interaction between two medications does not always mean that you

must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.

Overdose

Symptoms of Zetia overdose are not known but it can be harmful.

If you experience one of them call your doctor immediately.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Zocor is a cholesterol-lowering medication which used to treat high cholesterol levels in the blood. It works by blocking the production of cholesterol in the body, thus can help prevent conditions that can lead to heart attack, heart disease and hardening of the arteries, stroke, and vascular disease. This medication can also reduce these risks in people with diabetes, peripheral vascular disease, and a history of stroke. Use this medication during low fat diet to get the best result.

Dosage and direction

Take this medication orally with or without food/milk.

The recommended starting dose of Zocor for adults is 20 to 40 milligrams once a day in the evening. The dosage can be varied every 4 weeks.

The recommended starting dose for children 10 to 17 years old is 10 milligrams once a day in the evening. The dosage can be varied every 4 weeks, but should not exceed 40 mg a day. Girls must have been menstruate for at least 12 months before starting therapy with Zocor.

Children under 10 years old only after doctor permission.

Note: this instruction presented here just for review. It’s very necessary to consult with your doctor before using. It help you to get best results.

Precautions

Before taking Zocor consult with your doctor if your medical history include: history of alcoholism, liver disease, severe infection, kidney disease, low thyroid function, heart disease, allergies. Try to limit alcohol intake because it can increase side effects. Also note: Zocor may increase your risk for liver problems. During the treatment with Zocor you may to limit the amount of grapefruit or grapefruit juice you may eat or drink (less than 1 quart a day) , because grapefruit juice may increase your risk for serious side effects.

For woman: Zocor should not be used during pregnancy, becoming pregnancy or lactating. Do not use before breast-feeding without doctor’s permission.

Contraindications

Zocor is not allowed in patients with active liver disease or unexplained persistent elevations of serum transaminases or who are hypersensitivity to any component of this medication. Pregnancy and lactation. Atherosclerosis is a chronic process and the discontinuation of lipid-lowering medications during pregnancy should have little impact on the outcome of long-term therapy of primary hypercholesterolemia. Ability of inhibitors of HMG-CoA reductase such as Zocor can decrease the synthesis of cholesterol and possibly other products of the cholesterol biosynthesis pathway, so Zocor is contraindicated during pregnancy and in nursing mothers. Zocor should be administered to women of childbearing age only when such women are highly unlikely to become pregnant. If the patient conceve while taking this drug, Zocor should be discontinued immediately and the patient should be apprised of the potential hazard to the fetus

Possible side effect

They may include all types of an allergic reaction. Also the most possible side effects include:

muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine.

Less serious include:

mild stomach pain, gas, bloating, stomach upset, heartburn;

nausea;

constipation; or

diarrhea.

If you experience one of them stop using Serevent and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Zocor interact with such types of drugs as: danazol; gemfibrozil (Lopid), clofibrate, or fenofibrate;

niacin; nefazodone; cholestyramine or colestipol; warfarin; amiodarone, diltiazem, or verapamil;

erythromycin, clarithromycin, or telithromycin; an antifungal medication such as itraconazole, fluconazole, or ketoconazole; drugs that weaken your immune system such as cancer medicine or steroids, cyclosporine, sirolimus, tacrolimus, and others; HIV or AIDS medication such as amprenavir, indinavir, nelfinavir, ritonavir, lopinavir-ritonavir, or saquinavir. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.

Overdose

Overdose of Zocor is not danger for you life and iclude such symptoms: myalgia and red urine (in a severe overdose). If you experience one of them call your doctor immediately.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Atorvastatin is a cholesterol-lowering which used used to treat high cholesterol or to lower the risk of stroke, heart attack or other heart complications in patients with coronary heart disease or second type of diabetes. Atorvastatin helps to clear harmful low-density lipoprotein cholesterol out of the blood and by limiting the body’s ability to form new LDL cholesterol. Thus can help prevent hardening of the arteries and heart disease, conditions that can lead to vascular disease, heart attack, stroke.

Dosage and direction

Take it orally once a day with or without food. Atorvastatine should be taken with full glass of water.

The commonly dose for adults is 10 mg once daily.

The commonly dose for children 10 to 17 years of age is 10 mg once daily.

Using Atorvastatin in children less than 10 years of age is not recommended and dose must be determined by your family doctor.

Note: this instruction presented here just for review. It’s very necessary to consult with your doctor before using. It help you to get best results.

Precautions

People with diabetes, underactive thyroid glands, kidney disease, or muscle disease sometimes need additional tests before or during atorvastatin therapy since dosage adjustments may be required. Do not use large amounts of alcohol while taking this drug because it can worsen the adverse effects of this medicine on the liver. Atorvastatin should not be used during pregnancy, becoming pregnant or lactating without doctor’s advice. Do not use Atorvastatin before breast-feeding without doctor’s permission.

Contraindications

Atorvastatin is not allowed to people who have liver problems or unexplained abnormal liver function tests. Do not use it if you are taking an HIV protease inhibitor (eg, ritonavir), itraconazole, or mibefradil. Also Atorvastatin contraindicated if you are hypersensitive to any components of this medication, pregnancy or breast-feeding.

Possible side effect

They may include all types of an allergic reaction. Also the most possible side effects include:

muscle pain, tenderness, or weakness with fever or flu symptoms; or

nausea, clay-colored stools, stomach pain, low fever, jaundice, loss of appetite, dark urine.

Less serious include:

mild nausea or stomach pain, stomach upset, heartburn;

constipation, bloating, gas;

stuffy nose;

itching, skin rash;

headache.

If you experience one of them stop using Atorvastatin and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Atrovastatin interact with the following drugs: digoxin; erythromycin or clarithromycin; gemfibrozil or fenofibrate; niacin; an antifungal medication such as itraconazole, fluconazole, or ketoconazole; drugs that weaken your immune system such as cancer medicine or steroids, cyclosporine, sirolimus, tacrolimus, and others; HIV or AIDS medication such as indinavir, nelfinavir, ritonavir, lopinavir-ritonavir, or saquinavir. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.

Overdose

Symptoms of Atorvastatin is not known well but most possible include a severe drop in blood pressure and a faster heartbeat. If you experience one of them or any unusual symptoms call your doctor immediately.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Crestor is a cholesterol-lowering medication which used to lower cholesterol levels when diet and exercise alone have failed to work.

Dosage and direction

Take this medication with or without food, at any time once a day. Swallow each tablet whole with a drink of water/milk.

Commonly dose of Crestor is 5 to 40 mg. Dosage of 40 mg is using for patients not reaching LDL-C goal with 20 mg.

Hyperlipidemia, mixed dyslipidemia, hypertriglyceridemia, and atherosclerosis: Starting dose 10 mg. Cresor 20 mg is a starting dose for patients with LDL-C >190 mg/dL and aggressive lipid targets.

HoFH: Starting dose is 20 mg.

This drug is only a small part of a whole program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very carefully.

Note: this instruction presented here just for review. It’s very necessary to consult with your doctor before using. It help you to get best results.

Precautions

Do not take if you have any liver problems or have ever had a disease which affected your liver; if you have any kidney problems; if you have been told that you have a condition affecting your muscles called myopathy; if you are taking the immunosuppressive drug, cyclosporin; if you are pregnant or if there is a possibility that you may become pregnant; if you are breast-feeding. Consult with your doctor if you are taking any other medicines, including those which you may have bought over the counter. In particular tell your doctor if you are taking any of the following: gemfibrozil, cyclosporin, warfarin, antacids, erythromycin or an oral contraceptive.

Contraindications

Crestor is contraindicated in patients:

– with hypersensitivity to rosuvastatin or to any of the excipients;

– with active liver disease;

– with severe renal impairment;

– with myopathy;

– receiving concomitant ciclosporin;

– during pregnancy and lactation and in women of childbearing potential not using appropriate contraceptive measures;

The 40 mg dose is contraindicated in patients with pre-disposing factors for myopathy/rhabdomyolysis. Such factors include:

− moderate renal impairment;

− hypothyroidism;

− personal or family history of hereditary muscular disorders;

− previous history of muscular toxicity with another HMG-CoA reductase inhibitor or fibrate;

− alcohol abuse;

− situations where an increase in plasma levels may occur ;

− Asian patients;

− concomitant use of fibrates.

Possible side effect

They may include all types of an allergic reaction. Also the most possible side effects include:

muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine;

urinating more or less than usual, or not at all;

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

chest pain; or

swelling in your hands or feet.

Less serious include:

weakness, dizziness;

mild nausea, constipation, diarrhea;

sore throat, runny or stuffy nose;

memory loss;

headache; or

pain or burning when you urinate.

If you experience one of them stop using Crestor and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Do not take this medicine with any of the following medications: herbal medicines like red yeast rice or other medicines for high cholesterol

This medicine may also interact with the following medications: alcohol, antacids containing aluminum hydroxide or magnesium hydroxide, cyclosporine, niacin, warfarin.

Also note that interaction between two medications does not always mean that you

must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.

Overdose

The symptoms of a Crestor overdose are not known well. Most possible of them include: liver damage, kidney failure, pancreatitis, yellow skin (jaundice), serious breakdown of muscle (known as rhabdomyolysis). If you experience one of them call your doctor immediately.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.